Tripropylene Glycol (TPG)

Overview

Tripropylene Glycol (CAS No: 24800-44-0), also known as TPG, is a colorless, slightly odorous, viscous liquid. As a member of the propylene glycol family, this organic compound is widely used as a solvent and carrier in various industries. It is miscible with water, alcohols, and many organic solvents.

TPG is preferred in cosmetic, personal care, and paint industries due to its low vapor pressure and high boiling point. Its mild hygroscopic properties and low toxicity make it safe for use in products that come into contact with skin.

Applications

Tripropylene Glycol has a wide range of industrial and consumer applications:

Technical Specifications

Safety Information

Hazard Symbols and Statements

Flammable Skin and Eye Irritation Health Hazard Environmental Hazard

Personal Protective Equipment (PPE)

• Chemical-resistant gloves (nitrile or neoprene)
• Chemical safety goggles or face shield
• Adequate ventilation
• Chemical-resistant apron or work clothes
• Dust mask (in case of dust formation)

Storage Conditions

• Store in a cool, dry, well-ventilated area
• Store in stainless steel, polyethylene, or glass containers
• Store separately from oxidizing agents
• Storage temperature: 10-40°C
• Protect from moisture and direct sunlight

Fire Fighting

• Suitable extinguishing agents: Foam, dry chemical, CO₂, or water mist
• Use alcohol-resistant foam for large fires
• Intervention by trained personnel with appropriate respiratory protection
• Combustion products may contain carbon monoxide and carbon dioxide

Handling and Storage

Handling

• Ensure containers are tightly closed
• Ground during transfer to prevent static electricity buildup
• Avoid eating, drinking, or smoking
• Provide adequate ventilation in handling areas
• Keep "Flammable Liquid" label on transport containers

Storage

• Store in stainless steel, polyethylene, or glass containers
• Keep "Flammable Liquid" signs in storage area
• Use appropriate breathing vents in storage tanks
• Provide secondary containment for large quantities
• Maintain drainage systems in storage areas

Spill Response

• Remove exposed personnel from the area
• Use appropriate personal protective equipment
• Absorb spills with sand, chemical absorbent, or other absorbent materials
• Dispose of absorbed material appropriately
• Wash the area thoroughly with plenty of water and detergent

Regulatory Information

GHS Classification

• Flammable Liquid Category 4
• Skin Irritation Category 2
• Eye Irritation Category 2
• Aquatic Toxicity Category 3

Important Regulations

• REACH: Registered
• CLP: Compliant
• OSHA: Subject to Hazard Communication Standard
• NFPA 704: Health 1, Flammability 1, Reactivity 0

International Regulations

• European Union: Cosmetics Regulation (EC) No 1223/2009
• USA: FDA approved for food contact (21 CFR 175.300)
• China: Listed in IECSC
• Japan: Listed in ISHL

Environmental Information

Environmental Impact

Tripropylene Glycol has low toxicity in aquatic environments and is biodegradable. It degrades rapidly under appropriate conditions. Shows moderate mobility in soil and may enter groundwater. May be moderately harmful to aquatic organisms.

Biodegradation

• Air: 20-50 day half-life through photochemical reactions
• Water: Degrades within 5-15 days through microbial activity
• Soil: Degrades within 2-6 weeks through microbial activity
• Biological Oxygen Demand (BOD): 45% (28 days)
• Chemical Oxygen Demand (COD): 2.1 g O₂/g

Waste Management

• Not classified as hazardous waste
• Small quantities can be diluted with plenty of water and discharged to sewer
• Large quantities should be incinerated at licensed waste disposal facilities
• Dispose in accordance with local regulations
• Easily degraded in wastewater treatment plants

Frequently Asked Questions

How is Tripropylene Glycol produced?

TPG is produced through controlled hydration of propylene oxide with water. This process is carried out under specific catalyst and temperature/pressure conditions. Industrial-scale production typically uses propylene oxide hydration followed by purification processes.

What is the difference between TPG and PPG (Polypropylene Glycol)?

TPG (C₉H₂₀O₄) is a glycol ether containing three propylene oxide units, while PPG is a longer-chain polymer. TPG has lower molecular weight and sharper properties. PPG has higher viscosity and is used in different applications.

Is TPG safe for skin contact?

TPG is generally safe for use in products that contact skin, but prolonged or repeated exposure should be avoided. It may cause irritation in sensitive skin. In case of skin contact, wash thoroughly with plenty of water and soap.

What are the solvent properties of TPG?

TPG has the ability to dissolve various organic compounds. It is a good solvent for polar and semi-polar substances. Its low vapor pressure and high boiling point provide long-lasting solvent effect.

Is TPG suitable for food contact?

TPG has been approved by the FDA for food contact under certain conditions and concentrations. However, food applications should use specially purified versions manufactured for this purpose.